How to analyze a large data set with a limited memory.
TCGA data sets are so large and your computer might have memory errors. It is a physical limitation and you have to add RAM to solve the problem though, you can avoid the problem somehow.Strategies are;
- to divide sample groups (by center)
- to divide genes (by chromosome)
- to reduce samples (normal-tumor pairs only)
- to reduce genes (removing non-sense genes for the analysis)
In this case study, I'm showing the 4th way.
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