Subio Platform

Subio Platformは、RNA-Seqやマイクロアレイのデータ解析はもちろんのこと、測定装置の種類やメーカーを問わずさまざまなオミクスデータの比較・統合解析を行うのに最適なソフトウェアです。



  • Subio Platformのダウンロード数: 12,000以上
  • プラグインのラインセンス数: 3,000以上
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下のフォームに必要事項をご記入後、ダウンロードボタンをクリックしてSubio Platformをダウンロードしてください。


  • Windows 10または11 (64-bit) / macOS 10.14 Mojave 以降
  • 2 GHz 以上のプロセッサー
  • 4 GB 以上の RAM
  • 5 GB の空き容量のあるハードディスク
  • 1024 x 768 以上の画像解像度をサポートしているディスプレイ


* 必須項目


Subio Platform End User License Agreement version 1.4

This Agreement, and any new versions, between Subio and You, covers all Your use of Subio Platform and Plug-ins from any terminals. Unless You have another agreement directly with Subio that controls and alters your use or distribution of Subio Platform, the conditions of the applicable license agreements below apply to you.

1. Definitions.

this End User License Agreement, as may be renewed and/or amended from time to time.
You (or Your)
an individual or a legal entity exercising rights under, and complying with all of the terms and conditions of, this License or a future version of this License issued under Section2.8.
Subio Inc., headquartered in Amami island, Japan.
Plug-in Partner
an individual or a legal entity who develops and provides Plug-ins, which are distributed together with Subio Platform.
Subio Platform
Subio Platform, which Subio creates, owns and distributes exclusively. All Plug-ins depend on Subio Platform and they don't work alone nor even start without Subio Platform.
a software created by Subio or Plug-in Partners that works with, adds a variety of functionalities to and distributed together with Subio Platform. You will Activate a Plug-in to use it from a computer installing Subio Platform.
Activate (or Activation)
to authorize one computer to use a Plug-in for one year, by exercising a Serial Number.
Activation Key
a file created as a result of Activation, and it is necessary for Subio Platform to access to the Activated Plug-in.
Serial Number
Plug-in customers will purchase Serial Numbers from Subio or a reseller. Serial Number can be exercised only one time from a computer which is connected to the internet.

2. License and Restrictions

2.1 License of Subio Platform

Subject to the terms and conditions of this Agreement, Subio hereby grants You a limited, personal, non-commercial, non-exclusive, non-sublicensable, free of charge license to download, install and use Subio Platform on Your computer. You may use Subio Platform and Plug-ins anywhere like universities, research institutions, home or at work.

2.2 No Granting of Rights to Third Parties

You will not sell, assign, rent, lease, distribute, export, import, act as an intermediary or provider, or otherwise grant rights to third parties with regard to Subio Platform, Plug-ins or any part thereof.

2.3 No Modifications

You will not undertake, permit or authorize the modification, creation of derivative works, translation, reverse engineering, decompiling, disassembling or hacking of Subio Platform or any part thereof except to the extent permitted by law. Only one exception is that You are allowed reverse engineering of Subio.jar, Subio64.exe and jp.subio.plugins.b.jar.

2.4 Third Parties

Subio Platform incorporates and distributed together with software which are owned and controlled by third parties. Any such third party software falls under the scope of this Agreement. Any and all other third party software that may be distributed together with Subio Platform will be subject to You explicitly accepting a license agreement with that third party. You acknowledge and agree that You will not enter into a contractual relationship with Subio regarding such third party software and You will look solely to the applicable third party and not to Subio to enforce any of Your rights.

2.5 Use of Plug-ins

Subio Platform incorporates and distributed together with Plug-ins which are owned and controlled by Subio or Plug-in Partners. To use Plug-ins, You must purchase Serial Number for each Plug-in from Subio or resellers. If You buy them in Japan, You are also responsible for paying consumption tax. You will explicitly acknowledge the End User License Agreement of the Plug-in by its Activation. Once You have Activated a Plug-in, You may not change the expiration date and the authorized computer. You are not allowed to try, do nor inform any ways of Activation other than the instruction provided by Subio.

2.6 Prohibition of Plug-in Development

You are not allowed to create and distribute Plug-ins, unless You explicitly sign the Subio Plug-in Partner Agreement or an alternative agreement and comply with the terms and conditions thereof.

2.7 Exclusive Ownership

Any and all IP Rights in Subio Platform, contents of Subio website, all materials and documents which are created by Subio are and shall remain the exclusive property of Subio and/or its licensors. Nothing in this Agreement intends to transfer any such IP Rights to You.

2.8 New Versions of Subio Platform and Plug-ins

Subio, in its sole discretion, reserves the right to add additional features or functions, or to provide programming fixes, updates and upgrades, to Subio Platform and Plug-ins. Subio has no obligation to make available to You any subsequent versions of Subio Platform and Plug-ins. You may have to enter into a renewed version of this Agreement, in the event You want to download, install a new version of Subio Platform.

2.9 Suspension

Subio may, in its sole discretion and to the maximum extent permitted within Your jurisdiction, modify or discontinue or suspend Your ability to use any version of Subio Platform and Plug-ins, and/or disable any Subio Platform You may already have accessed or installed without any notice to You, for the repair, improvement, and/or upgrade of the underlying technology or for any other justifiable reason, including but not limited to, circumstances where You, at Subio's discretion, are in breach of this license, creating problems, possible legal liabilities, or engaging in fraudulent, immoral or illegal activities, or for other similar reasons.

3. Disclaimer of Warranties and Limitation of Liability

3.1 No Warranties

Installing Subio Platform enables You to manage, visualize and analyze Omics data. Subio cannot guarantee that You will always be able to get correct calculations and visualizations, nor can Subio guarantee that You can store data entirely and perfectly without inadequate modifications or losing integrity of the data. Subio Platform and Plug-ins are provided “as is” with no warranties whatsoever; Subio does not, either expressed, implied or statutory, make any warranties, claims or representations with respect to Subio Platform and Plug-ins, including, without limitation, warranties or conditions of quality, performance, non-infringement, merchantability, or fitness for use for a particular purpose. Subio further does not represent or warrant that Subio Platform and Plug-ins will always be available, accessible, uninterrupted, timely, secure, accurate, complete and error-free, nor does Subio warrant any quality of analysis with Subio Platform and Plug-ins.

3.2 Your own Risk

Maintenance of Your computer and backup of Your data is entirely responsibility of You. You may be exposed to information security risks by using Subio Platform and Plug-ins with on-line resources. You further acknowledge and agree that the entire risk arising out of the use or inability to use Subio Platform and Plug-ins remains with You, to the maximum extent permitted by law. You understand, therefore, that You use Subio Platform and Plug-ins at Your own risk.

3.3 No Liability

Subio Platform is being provided to You free of charge. You acknowledge and agree that Subio and its licensors and Subio staff will have no liability in connection with or arising from your use of Subio Platform and Plug-ins. Your only right or remedy with respect to any problems or dessatisfaction with Subio Platform and Plug-ins is to immediately uninstall and cease use of such Subio Platform and Plug-ins. Any indirect, incidental, special or consequential damages (including without limitation any loss of or corruption to data, interruption, computer failure or pecuniary loss) arising out of the use or inability to use Subio Platform and Plug-ins; and any loss of income, business or profits (whether direct or indirect) arising out of the use or inability to use Subio Platform and Plug-ins; any loss or damage which may be incurred by You as a result of;

  1. Any errors or incorrect calculations when using Subio Platform and Plug-ins;
  2. Any interruption or inability to use Subio Platform and Plug-ins or their functionalities due to network error or inaccessibility and unavailability of server;
  3. The suspension or termination of this agreement by You or by Subio for any reason; and
  4. The release or the decision not to release new versions of Subio Platform and Plug-ins to you.

The limitations on Subio's liability to You described above shall apply whether or not Subio or the Subio staff has been advised of the possibility of such losses or damages arising.

3.4 Jurisdiction's Limitations

As some jurisdictions do not allow some of the exclusions or limitations as set forth above, some of these exclusions or limitations may not apply to You. In such event the liability will be limited to the maximum extent possible within the applicable legislation.

4. Miscellaneous

4.1 Entire Agreement

The terms and conditions of this Agreement constitute the entire agreement between You and Subio with respect to the subject matter hereof and will supersede and replace all prior understandings and agreements, in whatever form, regarding the subject matter. Nothing in this clause shall exclude or restrict the liability of either You or Subio arising out of fraud or fraudulent misrepresentation.

4.2 Partial Invalidity

If any provision, or any part of a provision, is found by any court or administrative body of competent jurisdiction to be illegal, invalid or unenforceable, and the provision (or part-provision) in question is not of a fundamental nature, the legality, validity or enforceability of the remainder of the terms and conditions of this Agreement (including the remainder of the term which contains the relevant provision) shall not be affected.

4.3 No Waiver

The failure to exercise, or delay in exercising, a right, power or remedy provided by this Agreement or by law shall not constitute a waiver of that right, power or remedy. If Subio waives a breach of any provision of the terms and conditions of this Agreement shall not operate as a waiver of a subsequent breach of that provision, or as a waiver of a breach of any other provision.

4.4 No Assignment

You are not allowed to assign the terms and conditions or any rights hereunder. Subio is allowed at its sole discretion to assign the terms and conditions or any rights hereunder to any third party, without giving prior notice.

4.5 Applicable Law and Competent Court

The terms and conditions of this Agreement shall be governed by and interpreted in accordance with the laws of Japan and shall be subject to the jurisdiction of the courts of the district of Kagoshima.

4.6 Language

The original English version of this Agreement may have been translated into other languages. In the event of inconsistency or discrepancy between the English version and any other language version, the English language version shall prevail.

You expressly acknowledge that you have read this agreement and understand the rights, obligations, terms and conditions set forth herein. By installing Subio Platform, You expressly consent to be bound by its terms and conditions and grant to Subio the rights set forth herein.



ウェブ会議でSubio Platformのデモをさせていただきます。 Subio Platformがあなたにとって有用かどうかは、デモをご覧になってご判断ください。

Request a Demonstration

Subio Platformでできること

オミクスデータ解析ソフトというと、R(Bioconductor)やPythonなどの統計ツールを思い浮かべる人が多いと思いますが、実際のオミクス研究ではそれだけでなく、下記のようなユーティリティも必要です。 Subio Platformはこういった機能をすべて提供しながらも、GeneSpringのように高額のライセンス料はかかりません。 有料のプラグインも安価なので、ライセンス料が無料でも学習コストやメンテナンスコストが高くつくバイオインフォマティクスツールと比べても合理的です。 そして有料のプラグインが無くても、無料のSubio Platformだけで予備解析の作業はほとんど完遂できます

Subio Platformでは、独学する方のためにソフトウェアの使い方チュートリアル問題解決方法ケーススタディなどの情報を発信しています。 また、必要に応じて有料のデータ解析サービスオンライントレーニングも安価に受けられます。

それでは、Subio Platformの機能をご紹介しましょう。



グラフ上の点や線をマウスで囲うだけで、それが何の遺伝子か分かります。 逆に遺伝子名で検索すると、グラフにその遺伝子の発現パターンが示されます。 他にもさまざまなことが簡単な操作でできるので、コマンド操作よりも直感的にデータを理解できます。 さらに、各Viewerが相互に連携しているので、様々な視点からデータを眺めることができます。

オミクスデータはとても複雑なので、このような高度な視覚化ツールを使ってデータの特徴をきちんと理解する事がとても大事です。 残念ながらほとんどの技術講習では、統計解析ツールの使い方に注力しすぎて、視覚化ツールを軽視しています。 しかし、データを見て正しく理解する事こそ、解析の第一歩です。


Scatter Plot (Measurement) の使い方 詳細
Line Graph の使い方 詳細
Tree View の使い方 詳細
Pathway View の使い方 詳細
Genome View の使い方 詳細
Scatter Plot (Samples) の使い方 詳細
ベン図ツールの使い方 詳細


そのデータにあう適切な正規化・前処理を見つける 詳細
RNA-Seqデータの正規化の解説 詳細
なぜ対数比にして解析するのか 詳細
過度な正規化はしないほうが良い理由 ー RMAの教訓 詳細
なぜZ-score Normalizationを使うべきでないのか 詳細

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自分の実験データを、GEO(Gene Expression Omnibus)TCGA(The Cancer Genome Atlas)など公共データベース等から取得した大量のデータと併せて管理し、欲しい情報を簡単に取り出せるようにしておけばとても役に立つということは、疑いの余地がありません。 オミクスデータから一度の解析ですべての情報を引き出すことはできませんから、過去の実験データにも潜在的な価値が眠っています。

ただし、公共データベースに蓄積された様々な種類のデータを扱うには、より多くの知識と経験が必要で難易度が高いと言えます。 ご自身で再解析することが難しい場合は、データ解析サービスで対応しますのでご安心ください。


  • タブ区切りテキスト形式のテーブル(RNA-Seq、マイクロアレイ、DNAメチル化、プロテオミクスなど)
  • RNA-Seq FASTQファイル
  • BED/WIG/Bigwigファイル(ChIP-SeqやATAC-Seqなどの一次解析の結果)



RNA-Seq FASTQファイルのインポート 詳細
RNA-Seqのcount/TPM/FPKMなどのテーブルのインポート 詳細
Agilent Technologies社マイクロアレイデータのインポート 詳細
旧Affymetrix(現Thermo Fisher)社GeneChipデータのインポート 詳細
エクセルで持っている数値データのインポート 詳細
Bigwigデータのインポート 詳細


GEOに登録されているマイクロアレイデータのインポート 詳細
TCGAのRNA-Seqデータのインポート 詳細
TCGAのmiRNA-Seqデータのインポート 詳細
TCGAのDNAメチル化アレイデータのインポート 詳細


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われわれ人類は、まだオミクスデータの解析方法を知りません。 データをどのように扱って、どのように見れば重要な生物学的な意味を引き出せるのか、バイオインフォマティシャンだけでなく、多くの実験生物学者を交えたオープンな議論がもっともっと必要なのです。 しかし、バイオインフォマティクスツールの使い勝手の悪さから、誰でも議論に参加できるとは言い難い状況が続いています。

Subio PlatformからSSAファイルを出力すれば、生データ・途中結果・最終結果などすべてまとめて、たった一つのファイルで渡すことができます。 SSAファイルを受け取った共同研究者は、Subio Platformにインポートするだけですべてを再構築できます。 かれらは即座に解析結果を検討し、それぞれ独自の視点から再解析を行うことができるのです。 PDFやエクセルで解析結果を受け渡すのに比べて、格段に深いディスカッションおよび共同作業が可能になります。

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バイオインフォマティクスがオープンソースや無料のソフトウェアに支えられてきたことは事実ですが、このようなツールの抱える問題も明らかになってきます。 それは、プロジェクトの終了や開発者の転籍などで短命なものが多く、長い時間のかかる研究の途中で使えなくなるツールが続出しているということです。 OSやミドルウェアがさまざまな脅威に対抗するために常に更新されている中、メンテナンスを放棄されたバイオインフォマティクスツールが後を絶ちません。 アカデミックの世界ではバイオインフォマティシャンの業績評価が新しいツールの開発に偏っており、既存ツールのメンテナンスに対するインセンティブが乏しいことが原因です。

この問題への解決策として、プラグインユーザーから少額のライセンス料を受け取ることで自律的に持続可能な運営体としてSubioを設立しました。 マイクロアレイの登場以降、さまざまな測定装置や解析ソフトが現れては消えていく中、当初の目的からブレることなくメンテナンスを続けてきた結果、様々な種類のオミクスデータを蓄積し統合解析することができる安定したソフトウェア基盤として唯一無二の存在となっています。


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Subio Platformは、RやPythonなどが提供していない便利な機能やインタラクティブなユーザーインターフェースを提供していますが、逆に、RやPythonなどが提供する高度な統計解析機能は持っていません。 しかし、Subio Platformからデータを出力して、RやPythonのツールを使って計算を実行させることが簡単にできます。

Subio Platformと各種バイオインフォマティクスツールは、競合するのではなく、互いに機能を補完しあえます。 これらを組みあわせることで、包括的な解析システムをとても安価に構築できるのです。


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Subio Platform自体がフリーなので、解析用PCは1台でも、各自が自分のデータを持ち帰って自分のPCで解析できること。










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